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Learning Zone DP
Overview
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| Treatment | Notes |
| Aminoglycoside antibiotics | |
| Beta-blockers | |
| Botulinum toxin | Should be avoided |
| Chloroquine/hydroxychloroquine | May trigger de novo MG or worsen existing symptoms |
| Corticosteroids | Monitor carefully in first 2 weeks for transient worsening of symptoms |
| Desferrioxamine (deferoxamine) | |
| ᴅ-Penicillamine | Believed to trigger new MG and should be avoided |
| Fluoroquinolone antibiotics | Carry FDA black box warning for worsening MG. Avoid or use with caution |
| Immune checkpoint inhibitors | May trigger de novo MG or worsen existing symptoms, but important cancer treatments. Use with caution if needed |
| Iodinated radiological contrast agents | Older agents reportedly worsen MG symptoms; newer agents may carry less risk. Use with caution |
| Macrolide antibiotics | |
| Magnesium | Potentially high risk if given intravenously. Avoid use if possible |
| Procainamide | |
| Quinine | |
| Statins | May occasionally trigger or worsen MG |
| Telethromycin | Carries black-box FDA warning for severe, often fatal MG worsening. Should not be used |
| Live-attenuated vaccines | Contraindicated in patients taking immunosuppressive treatments |
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